Henrikh Mkhitaryan scored on his Roma introduction to help new boss Paulo Fonseca with a win over Sassulo.
The Armenia international, who joined the funds club on loan scored his side’s third goal as the visitors had been put to the sword at the first half.
Roma had been 4-0 up due to Bryan Cristantes header, a volley in Edin Dzeko, a written finish along with Mkhitaryan’s low attack from Justin Kluivert.
The visitors came Domenico Berardi in the second half but it was too little too late.
Roma goes into seventh position on five points, four supporting leaders Inter Milan, while Sassuolo are 12th after taking three points.
Earlier in the day, hopefuls stunned Lazio since they came from behind to win 2-1 thanks to Jasmin Kurtic winner.
Bologna also went joint-second after pulling off a remarkable comeback in Brescia, recovering to win 4-3 later Daniele Dessena was sent off after the break.
Duvan Zapata watched a stunning stoppage-time strike to make a 2-1 success at Genoa to Atalanta, although Cagliari won 3-1 away to Parma.
Joan Jordan’s goal was to triumph at Alaves and then go to the top of La Liga for the first time this season.
Atletico Madrid’s 3-2 defeat at Real Sociedad on Saturday night finished Sevilla and the league’s just perfect record took good great advantage of the slip up having a success.
Jordan curled in a free-kick that was fantastic with 25 minutes on the clock and it proved enough at the country, since Sevilla passed up many chances to double their lead.
Remain mid-table and alaves didn’t get a single shot on goal.
Elsewhere, Celta Vigo had Saenz and Beltran sent in the 29 minutes to Granada at home and suffered a defeat to the newly-promoted side.
The aim of califa Koulibaly was enough to move up Nantes to win over Stade Reims, that missed the chance remain and to move into the upper half.
Elsewhere, Bournemouth winger Max Gradel along with ex-Leeds played against his former club Toulouse’s 2-2 draw in which the hosts clawed back by a shortage.
David Wagner’s Schalke came out of succeed 5-1 at second-bottom Paderborn, a win which moved them up to sixth at the table with seven points.
Cauly headed encouraged Paderborn in front in the eighth minute before Salif Sane equalised in the 33rd with a header of their own.
Suat Serder shot gave the lead four minutes setup by Everton full-back Jonjoe Kenny made it 3-1 in the 71st minute.
Substitute Ahmed Kutucu and Harit netted in the 85th and 83rd minutes respectively wrapped up.
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